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Peptide sequence: MAAEDVVATG ADPSDLESGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ
Sequence homology: Cow: 79%; Dog: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rabbit: 86%; Rat: 93%
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dap1; HGNC:16090; IZA; Membrane-associated progesterone receptor component 1; mPR; progesterone binding protein
基因别名: HPR6.6; MPR; PGRMC; PGRMC1
UniProt ID: (Human) O00264
Entrez Gene ID: (Human) 10857