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产品信息
PA5-81238
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the center region of the Human PIK3R2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2788465
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human PIK3R2.
靶标信息
Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
基因别名: MPPH; MPPH1; p85; p85-BETA; P85B; PIK3R2
UniProt ID: (Human) O00459
Entrez Gene ID: (Human) 5296
GTPase activator activity
protein binding
1-phosphatidylinositol-3-kinase activity
protein phosphatase binding
receptor tyrosine kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
kinase modulator
cellular glucose homeostasis
phosphatidylinositol biosynthetic process
insulin receptor signaling pathway
regulation of autophagy
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
protein transport
cellular response to insulin stimulus
response to endoplasmic reticulum stress
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of transcription factor import into nucleus
positive regulation of GTPase activity
regulation of phosphatidylinositol 3-kinase activity
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
regulation of small GTPase mediated signal transduction
positive regulation of glucose import in response to insulin stimulus
