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产品信息
PA5-52600
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.15 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2645587
产品详细信息
Immunogen sequence: SFTFFNSMSP LSSQSMFSAP SSISSMTMPS SMGPGAVPGM PNSGLNNINN LTGSSLNSAM SPGACPYGTP ASPYSVYRDT CNSSLASLRL KSKQHSS
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
靶标信息
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
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生物信息学
蛋白别名: hindlimb expressed homeobox protein backfoot; Hindlimb-expressed homeobox protein backfoot; Homeobox protein PITX1; OTX; paired-like homeodomain 1; Paired-like homeodomain transcription factor 1; pituitary homeo box 1; Pituitary homeobox 1; pituitary otx-related factor
基因别名: BFT; CCF; LBNBG; PITX1; POTX; PTX1
UniProt ID: (Human) P78337
Entrez Gene ID: (Human) 5307
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
protein binding
homeodomain transcription factor
skeletal system development
transcription from RNA polymerase II promoter
anatomical structure morphogenesis
branchiomeric skeletal muscle development
pituitary gland development
embryonic hindlimb morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
myoblast fate commitment
cartilage development
