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PKD2 Antibody (A300-074A-T) in WB
Detection of human PKD2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PKD2 antibody A300-074A-M (lot A300-074A-M-1) used at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A300-074A-T
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 825 and C-term
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
靶标信息
PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: nPKC-D2; Serine/threonine-protein kinase D2
基因别名: HSPC187; nPKC-D2; PKD2; PRKD2
UniProt ID: (Human) Q9BZL6
Entrez Gene ID: (Human) 25865
angiogenesis
positive regulation of endothelial cell proliferation
adaptive immune response
protein phosphorylation
cell adhesion
cell death
positive regulation of endothelial cell migration
peptidyl-serine phosphorylation
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-2 production
positive regulation of interleukin-8 production
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
intracellular signal transduction
cellular response to vascular endothelial growth factor stimulus
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
positive regulation of blood vessel endothelial cell migration
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
endothelial tube morphogenesis
positive regulation of ERK1 and ERK2 cascade
protein kinase D signaling
mitophagy in response to mitochondrial depolarization
positive regulation of histone deacetylase activity
positive regulation of intracellular signal transduction
positive regulation of DNA biosynthetic process
positive regulation of endothelial cell chemotaxis
