Bethyl Laboratories

PKD2 Polyclonal Antibody

查看其他20个PRKD2抗体

产品信息

IHC-00570

应用

建议稀释比

已发表文章

免疫组化 (IHC)

1:100-1:500

-

免疫组化（石蜡） (IHC (P))

1:100-1:500

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Region between residues 825 and the C-terminus (residue 878).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

TBS, pH 7.0 to 8.0, with 0.1% BSA

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Wet ice

产品详细信息

The recommended shelf life for this product is 1 year from date of receipt.

靶标信息

PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: nPKC-D2; Serine/threonine-protein kinase D2

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基因别名: HSPC187; nPKC-D2; PKD2; PRKD2

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UniProt ID: (Human) Q9BZL6

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Entrez Gene ID: (Human) 25865

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protein kinase activity protein serine/threonine kinase activity protein kinase C activity protein binding ATP binding metal ion binding non-receptor serine/threonine protein kinase

参与通路

angiogenesis positive regulation of endothelial cell proliferation adaptive immune response protein phosphorylation cell adhesion cell death positive regulation of endothelial cell migration peptidyl-serine phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of interleukin-2 production positive regulation of interleukin-8 production positive regulation of CREB transcription factor activity positive regulation of peptidyl-serine phosphorylation intracellular signal transduction cellular response to vascular endothelial growth factor stimulus positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway positive regulation of blood vessel endothelial cell migration positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of transcription from RNA polymerase II promoter protein autophosphorylation vascular endothelial growth factor receptor signaling pathway T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity endothelial tube morphogenesis positive regulation of ERK1 and ERK2 cascade protein kinase D signaling mitophagy in response to mitochondrial depolarization positive regulation of histone deacetylase activity positive regulation of intracellular signal transduction positive regulation of DNA biosynthetic process positive regulation of endothelial cell chemotaxis