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产品信息
H00001263-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLK3 (NP_004064.2, 1 a.a. approximately 646 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).^M
^M
The Isotype of this product is composed of an IgG Mixture.^M
^M
Immunogen sequence: MEPAAGFLSP RPFQRAAAAP APPAGPGPPP SALRGPELEM LAGLPTSDPG RLITDPRSGR TYLKGRLLGK GGFARCYEAT DTETGSAYAV KVIPQSRVAK PHQREKILNE IELHRDLQHR HIVRFSHHFE DADNIYIFLE LCSRKSLAHI WKARHTLLEP EVRYYLRQIL SGLKYLHQRG ILHRDLKLGN FFITENMELK VGDFGLAARL EPPEQRKKTI CGTPNYVAPE VLLRQGHGPE ADVWSLGCVM YTLLCGSPPF ETADLKETYR CIKQVHYTLP ASLSLPARQL LAAILRASPR DRPSIDQILR HDFFTKGYTP DRLPISSCVT VPDLTPPNPA RSLFAKVTKS LFGRKKKSKN HAQERDEVSG LVSGLMRTSV GHQDARPEAP AASGPAPVSL VETAPEDSSP RGTLASSGDG FEEGLTVATV VESALCALRN CIAFMPPAEQ NPAPLAQPEP LVWVSKWVDY SNKFGFGYQL SSRRVAVLFN DGTHMALSAN RKTVHYNPTS TKHFSFSVGA VPRALQPQLG ILRYFASYME QHLMKGGDLP SVEEVEVPAP PLLLQWVKTD QALLMLFSDG TVQVNFYGDH TKLILSGWEP LLVTFVARNR SACTYLASHL RQLGCSPDLR QRLRYALRLL RDRSPA
靶标信息
PLK3 is a member of the polo family of serine/threonine kinases. PLK3 is involved in the regulation of M phase in the cell cycle. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytokine-inducible serine/threonine-protein kinase; FGF-inducible kinase; PLK-3; Polo-like kinase 3; Proliferation-related kinase; Serine/threonine-protein kinase PLK3
基因别名: CNK; FNK; PLK-3; PLK3; PRK
UniProt ID: (Human) Q9H4B4
Entrez Gene ID: (Human) 1263
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
response to reactive oxygen species
protein phosphorylation
apoptotic process
response to osmotic stress
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic cell cycle checkpoint
endomitotic cell cycle
response to radiation
cytoplasmic microtubule organization
regulation of cytokinesis
negative regulation of apoptotic process
protein kinase B signaling
mitotic G1/S transition checkpoint
regulation of cell division
Golgi disassembly
positive regulation of intracellular protein transport
regulation of signal transduction by p53 class mediator
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
