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Immunogen sequence: PRPPARITGV GAVPLPASGN SFDVRPSQGY RRRRGRGQHR RGGVARAGSR GSRKRKRHTF CYSCG
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 50%.
The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. There are reports of the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Paraneoplastic antigen Ma3; paraneoplastic cancer-testis-brain antigen
基因别名: MA3; MA5; PNMA3
UniProt ID: (Human) Q9UL41
Entrez Gene ID: (Human) 29944