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Invitrogen

PRMT8 Polyclonal Antibody

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1 篇参考文献
查看其他5个PRMT8抗体
说明书
实验方案
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说明书
实验方案
技术支持

产品信息

PA5-120639

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
查看1篇已发表文章 1篇已发表文章

酶联免疫吸附实验 (ELISA)

1 µg/mL
-
产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3).
查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

2.85 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2914211

产品详细信息

Positive test controls include: 293T, Mouse brain, Rat brain. The target is usually found in the following locations: Cell membrane, Cytoplasmic side, Lipid-anchor.

Immunogen sequence: VIFARDKWLK PGGLMFPDRA ALYVVAIEDR QYKDFKIHWW ENVYGFDMTC IRDVAMKEPL VDIVDPKQVV TNACLIKEVD IYTVKTEELS FTSAFCLQIQ RNDYVHALVT YFNIEFTKCH KKMGFSTAPD APYTHWKQTV FYLEDYLTVR RGEEIYGTIS MKPNAKNVRD LDFTVDLDFK G

靶标信息

Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: arginine methyltransferase 8; heterogeneous nuclear ribonucleoprotein methyltransferase-like 4; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4; HMT1 hnRNP methyltransferase-like 3; protein arginine N-methyltransferase 4; Protein arginine N-methyltransferase 8

基因别名: HRMT1L3; HRMT1L4; PRMT8

UniProt ID: (Human) Q9NR22, (Mouse) Q6PAK3

Entrez Gene ID: (Human) 56341, (Mouse) 381813, (Rat) 688502

功能
protein binding histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity identical protein binding protein homodimerization activity protein heterodimerization activity rRNA (adenine-N6,N6-)-dimethyltransferase activity protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity RNA methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity protein methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity protein-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity transferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity histone methyltransferase activity (H4-R3 specific) P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity molecular_function protein modifying enzyme
参与通路
regulation of transcription, DNA-templated histone methylation peptidyl-arginine methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine histone arginine methylation regulation of protein binding protein methylation methylation histone H4-R3 methylation biological_process
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