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产品信息
PA5-88644
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 127-416 of human PRP19 (NP_0553171)
偶联物
形式
Liquid
浓度
1.54 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805050
产品详细信息
Immunogen sequence: AREALATLKP QAGLIVPQAV PSSQPSVVGA GEPMDLGELV GMTPEIIQKL QDKATVLTTE RKKRGKTVPE ELVKPEELSK YRQVASHVGL HSASIPGILA LDLCPSDTNK ILTGGADKNV VVFDKSSEQI LATLKGHTKK VTSVVFHPSQ DLVFSASPDA TIRIWSVPNA SCVQVVRAHE SAVTGLSLHA TGDYLLSSSD DQYWAFSDIQ TGRVLTKVTD ETSGCSLTCA QFHPDGLIFG TGTMDSQIKI WDLKERTNVA NFPGHSGPIT SIAFSENGYY LATAADDSSV; Positive Samples: HepG2, Jurkat, HeLa, Mouse heart, Rat brain; Cellular Location: Cytoplasm, Lipid droplet, Nucleus, cytoskeleton, nucleoplasm, spindle
靶标信息
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPso4; Neuronal differentiation-related gene protein; Nuclear matrix protein 200; nuclear matrix protein NMP200 related to splicing factor PRP19; nuclear matrix protein SNEV; Pre-mRNA-processing factor 19; prp19 beta; PRP19/PSO4 homolog; PRP19/PSO4 pre-mRNA processing factor 19 homolog; psoralen 4; RING-type E3 ubiquitin transferase PRP19; Senescence evasion factor
基因别名: AA617263; AL024362; D19Wsu55e; hPSO4; NMP200; PRP19; PRPF19; PSO4; SNEV; UBOX4
UniProt ID: (Human) Q9UMS4, (Mouse) Q99KP6, (Rat) Q9JMJ4
Entrez Gene ID: (Human) 27339, (Mouse) 28000, (Rat) 246216
protein binding
ligase activity
ubiquitin-ubiquitin ligase activity
identical protein binding
ubiquitin protein ligase activity
ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
RNA processing factor
protein polyubiquitination
spliceosomal tri-snRNP complex assembly
spliceosomal complex assembly
mRNA splicing, via spliceosome
inner cell mass cell proliferation
transcription-coupled nucleotide-excision repair
double-strand break repair via nonhomologous end joining
lipid biosynthetic process
proteasomal protein catabolic process
cellular protein localization
negative regulation of neuron differentiation
positive regulation of mRNA splicing, via spliceosome
positive regulation of astrocyte differentiation
protein K63-linked ubiquitination
signal transduction involved in DNA damage checkpoint
generation of catalytic spliceosome for first transesterification step
DNA repair
mRNA processing
cellular response to DNA damage stimulus
RNA splicing
protein ubiquitination
positive regulation of neuron differentiation
