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产品信息
PA5-60499
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human PRPS1. Recombinant protein control fragment (Product #RP-100426).
偶联物
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2645980
产品详细信息
Immunogen sequence: LHASQIQVSV EAKYWCLKGG RKGLMMLKTA EKP
Highest antigen sequence identity to the following orthologs: Mouse - 36%, Rat - 39%.
靶标信息
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deafness 2, perceptive, congenital; deafness, X-linked 2, perceptive, congenital; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); Phosphoribosyl pyrophosphate synthase I; PPRibP; PRS-I; ribose-phosphate diphosphokinase 1; Ribose-phosphate pyrophosphokinase 1
基因别名: ARTS; CMTX5; DFN2; DFNX1; PPRibP; PRPS1; PRS-I; PRSI
UniProt ID: (Human) P60891
Entrez Gene ID: (Human) 5631
5-phosphoribose 1-diphosphate biosynthetic process
purine nucleobase metabolic process
purine nucleotide biosynthetic process
AMP biosynthetic process
pyrimidine nucleotide biosynthetic process
nervous system development
phosphorylation
organ regeneration
urate biosynthetic process
hypoxanthine biosynthetic process
