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Immunogen sequence: IHRTSSTLRR RSRTTPGPEE GPSQKVDRAP QPTLVVMLED IASPRPPAEG FIDETPNFII PAQRAEPMRI VRQPTPPPGD LEPPFQPSAL PADPLESPPT APDP
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 49%.
The protein encoded by this gene tethers heterochromatin to the nuclear laminar scaffold by binding heterochromatin protein 1 (HP1) and the nuclear lamina. The tether is broken during mitosis and reforms quickly after mitosis, with the encoded protein first binding HP1 and then attaching to the nuclear lamina. This protein also has been shown to promote MyoD activity and skeletal myogenesis. Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。