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Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C21-LRP; Chromosome 21 leucine-rich protein; Down syndrome critical region gene 2; Down syndrome critical region protein 2; leucine rich protein C21-LRP; PAC-1; Pba1; proteasome (prosome, macropain) assembly chaperone 1; proteasome assembling chaperone 1; Proteasome assembly chaperone 1; Proteasome chaperone homolog 1
基因别名: C21LRP; DSCR2; LRPC21; PAC-1; PAC1; PSMG1
UniProt ID: (Human) O95456
Entrez Gene ID: (Human) 8624