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Product Details
PA1-4135
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2237892
Product Specific Information
PA1-4135 detects Patched 2 (PTCH2) in human and mouse samples.
PA1-4135 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing PTCH2 in fetal brain lysate.
The PA1-4135 immunogen is a synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2.
Target Information
Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: patched homolog 2; Protein patched homolog 2; PTC2; RP11-269F19.8
Gene Aliases: PTC2; PTCH2; UNQ560/PRO1121/PRO57079
UniProt ID: (Human) Q9Y6C5, (Mouse) O35595
Entrez Gene ID: (Human) 8643, (Mouse) 19207
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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