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The antibody detects endogenous levels of total PTPN4 protein.
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signaling downstream of the glutamate receptors through tyrosine dephosphorylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MEG; megakaryocyte phosphatase; megakaryocyte protein-tyrosine phosphatase; protein tyrosine phosphatase MEG1; protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte); Protein-tyrosine phosphatase MEG1; PTP PTPMEG1; PTPase-MEG1; Testis-enriched protein tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 4
基因别名: hPTP-MEG; MEG; Ptn4; PTPMEG; PTPMEG1; PTPN4; TEP; TEP/mPTPMEG
UniProt ID: (Human) P29074, (Mouse) Q9WU22
Entrez Gene ID: (Human) 5775, (Mouse) 19258