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Antibodies Inc
Pan-Gamma-Protocadherin Monoclonal Antibody (N159/5), FL650
产品信息
75-185-FL650
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N159/5
抗原
Fusion protein corresponding to amino acids 808-931 (C-terminal cytoplasmic constant domain) of mouse Gamma-protocadherin-A1 that is shared by all 22 Gamma-protocadherins (A subfamily amino acids ~807-930, B subfamily amino acids ~789-912 and C subfamily amino acids ~818-941); produced recombinantly in E. Coli.
偶联物
FL650
激发/发射光谱
655/676 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3' RACE product; Pan-Gamma-Protocadherin-A; PCDH gamma A; PCDH-gamma-A; PCDH-gamma-A4; PCDHGA; pcdhga4; protocadherin 13; protocadherin 2; protocadherin gamma A12; protocadherin gamma B2; protocadherin gamma B6; protocadherin gamma C-VI; protocadherin gamma subfamily A, 12; protocadherin gamma subfamily C, 3; protocadherin gamma-A1; protocadherin gamma-A10; protocadherin gamma-A11; protocadherin gamma-A2; protocadherin gamma-A3; Protocadherin gamma-A4; protocadherin gamma-A5; protocadherin gamma-A6; protocadherin gamma-A7; protocadherin gamma-A8; protocadherin gamma-A9; protocadherin gamma-B1; protocadherin gamma-B2; protocadherin gamma-B4; protocadherin gamma-B5; protocadherin gamma-B6; protocadherin gamma-B7; protocadherin gamma-C4; protocadherin gamma-C5
基因别名: mKIAA0588; mKIAA4054; pc2c; PC43; Pcdh13; Pcdh2; Pcdhga4
UniProt ID: (Mouse) Q91XY4
Entrez Gene ID: (Mouse) 93709, (Mouse) 93722, (Mouse) 93723, (Mouse) 93724, (Mouse) 93710, (Mouse) 93711, (Mouse) 93712, (Mouse) 93713, (Mouse) 93714, (Mouse) 93715, (Mouse) 93716, (Mouse) 93717, (Mouse) 93699, (Mouse) 93700, (Mouse) 93701, (Mouse) 93702, (Mouse) 93703, (Mouse) 93704, (Mouse) 93706, (Mouse) 93707, (Mouse) 93708
