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NeoBiotechnologies
Positive Control:Ramos or Raji cells. Human tonsil or lymph node.
Cellular Location: Cell surface
MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ75017; FLJ76359; HLA-D; HLA-DQ; HLA-DR; MHC Class 2; MHC class II; MHC HLA-D; MHC II HLA; XXbac-BPG161M6.1