Fabgennix

Pannexin 1 Polyclonal Antibody, FITC

产品信息

PANX1-FITC

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

1:10,000

免疫沉淀 (IP)

1:50-1:250

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide taken within amino acid region from human Pannexin 1 protein

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

0.5-1.5 mg/mL

纯化类型

Affinity chromatography

保存液

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。