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Peptide sequence: VLEGNPEVGS PRTSDLQHRG NKGSCVLSSP GEDAQPGEEP IKYGELIVLG
Sequence homology: Cow: 92%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 93%; Rat: 93%
Pellino 1 is the mammalian homologue of Pellino, a Drosophila Pelle-interacting protein. Pelle is a serine-threonine kinase through which Toll signaling can occur. Pellino 1 can activate c-Jun, Elk-1 and NF-kB, whereas Pellino 3 can only activate c-Jun and Elk-1(2).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase pellino homolog 3; MGC35521; pellino homolog 3; Pellino-3; protein pellino homolog 3
基因别名: PELI3
UniProt ID: (Human) Q8N2H9
Entrez Gene ID: (Human) 246330