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Pepsin A Antibody (PA5-103156) in ICC/IF
Immunofluorescent analysis of Pepsin A in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Pepsin A polyclonal antibody (Product # PA5-103156) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-103156
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PGA4(Accession P0DJD7), corresponding to amino acid residues N352-A388.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852526
产品详细信息
Antibody detects endogenous levels of total Pepsin A.
靶标信息
Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Pepsin A is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. Pepsin A is inhibited by ovUS-1, a uterine serpin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: pepsin A; Pepsin A-3; Pepsin A-4; Pepsin A-5; Pepsin F; pepsinogen 5, group I; pepsinogen A3; pepsinogen A4; pepsinogen A5; pepsinogen F; Pepsinogen-3; Pepsinogen-4; Pepsinogen-5
基因别名: 1110035E17Rik; Pepf; Pg5; PGA3; PGA4; PGA5
UniProt ID: (Human) P0DJD8, (Human) P0DJD7, (Human) P0DJD9, (Mouse) Q9D106
Entrez Gene ID: (Human) 643834, (Human) 643847, (Human) 5222, (Mouse) 58803
