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Antibody detects endogenous levels of ATRIP only when phosphorylated at Serine 68.
ATRIP is an 86 kDa protein that is phosphorylated by ATR, regulates ATR expression, and is an essential component of the DNA damage checkpoint pathway. It localizes to the intranuclear foci after DNA damage or inhibition of replication.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATM and Rad3 related interacting protein; ATM and Rad3-related-interacting protein; ATR IP; ATR-interacting protein; DNase III; DRN3; FLJ12343
基因别名: 6620401K05Rik; AGS1; ATRIP
UniProt ID: (Human) Q8WXE1, (Mouse) Q8BMG1
Entrez Gene ID: (Human) 84126, (Rat) 301014, (Mouse) 235610