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Positive Samples: 293T
Immunogen sequence: SMSGL
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acaca; ACC-alpha; ACC1; Acetyl-CoA carboxylase 1; Acetyl-CoA carboxylase 265; Acetyl-Coenzyme A carboxylase alpha; EC 6.3.4.14; EC 6.4.1.2
基因别名: A530025K05Rik; ACAC; ACACA; ACACAD; ACC; ACC1; ACCA; Gm738
UniProt ID: (Human) Q13085, (Mouse) Q5SWU9, (Rat) P11497
Entrez Gene ID: (Human) 31, (Mouse) 107476, (Rat) 60581