Invitrogen

Phospho-Acetyl-CoA Carboxylase (Ser79) Recombinant Rabbit Monoclonal Antibody (RM270)

Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody (MA5-27974) in IHC (P)

Immunohistochemistry analysis of formalin fixed and paraffin embedded Human breast cancer tissue sections usingPhospho-Acetyl-CoA Carboxylase (Ser79) Recombinant Monoclonal antibody (Product # MA5-27974) at a dilution of 1:5,000.

Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody in Western Blot (WB)

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产品信息

MA5-27974

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

RM270

抗原

A phospho-peptide corresponding to human Phospho- Acetyl CoA Carboxylase (Ser79)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS with 1% BSA, 50% glycerol

内含物

0.09% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2744989

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。