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Phospho-Annexin A2 (Ser26) Antibody (PA5-37474) in WB
IUBMB life 2021 -
2 FIGURE PKC phosphorylates ANXA2 on Ser25 side chain. (a) Purified recombinant GST, GST-ANXA2, and GST-TIMAP proteins were incubated with or without active PKCalpha for 30 min. Amount of loaded proteins were verified by SDS-PAGE followed by Coomassie staining. Phosphorylation of proteins was analyzed by western blot using anti-phosphoSer PKC substrate and phospho-Ser25 annexin A2-specific antibodies. (b) P... View More
产品信息
PA5-37474
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Bovine,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide sequence around phosphorylation site of Serine 26 (Y-G-S(p)-V-K) derived from Human ANXA2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2554083
产品详细信息
A suggested positive control for Western blot is HepG2 or JK cells.^M
The homology between synthetic peptide sequence and Mouse/Rat is 100%.
靶标信息
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; epididymis secretory protein Li 270; Lipocortin II; p36; PAP-IV; Placental anticoagulant protein IV; Protein I
基因别名: ANX2; ANX2L4; ANXA2; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV
UniProt ID: (Human) P07355
Entrez Gene ID: (Human) 302
protease binding
calcium ion binding
protein binding
calcium-dependent phospholipid binding
phosphatidylinositol-4,5-bisphosphate binding
cytoskeletal protein binding
Rab GTPase binding
phospholipase A2 inhibitor activity
receptor activator activity
S100 protein binding
poly(A) RNA binding
calcium-dependent protein binding
cadherin binding involved in cell-cell adhesion
calcium-binding protein
angiogenesis
membrane raft assembly
positive regulation of protein phosphorylation
negative regulation of receptor internalization
membrane budding
body fluid secretion
collagen fibril organization
positive regulation of vesicle fusion
negative regulation of low-density lipoprotein particle receptor catabolic process
osteoclast development
fibrinolysis
negative regulation of catalytic activity
positive regulation of fibroblast proliferation
positive regulation of binding
protein heterotetramerization
protein targeting to plasma membrane
response to thyroid hormone
cell-cell adhesion
negative regulation of receptor binding
positive regulation of receptor activity
