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Phospho-EphA3 (Tyr602) Antibody (PA5-106128) in WB
Western blot analysis of Phospho-EphA3 (Tyr602) in EGF treated HeLa cell lysate (absence (-) or presence (+) of non-phospho and phospho peptide). Samples were incubated with Phospho-EphA3 (Tyr602) polyclonal antibody (Product # PA5-106128).
产品信息
PA5-106128
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human EPHA3(Accession P29320), corresponding to amino acid residues around phosphorylated Tyr602.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2817526
产品详细信息
Antibody detects endogenous levels of EPHA3 only when phosphorylated at Tyr602.
靶标信息
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands and receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 binds ephrin-A ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EK4; EPH-like kinase 4; Eph-like tyrosine kinase 1; Ephrin type-A receptor 3; H TYRO4; HEK; Human embryo kinase; human embryo kinase 1; rEK4; testicular tissue protein Li 64; TYRO4 protein tyrosine kinase; Tyrosine-protein kinase receptor ETK1; tyrosine-protein kinase receptor REK4; Tyrosine-protein kinase TYRO4
基因别名: AW492086; Cek4; EK4; End3; EPHA3; ETK; ETK1; HEK; HEK4; Mek4; Rek4; TYRO4
UniProt ID: (Human) P29320, (Rat) O08680
Entrez Gene ID: (Human) 2042, (Mouse) 13837, (Rat) 29210
GPI-linked ephrin receptor activity
protein binding
ATP binding
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
molecular_function
transmembrane signal receptor
cell adhesion
regulation of epithelial to mesenchymal transition
positive regulation of neuron projection development
cell migration
peptidyl-tyrosine phosphorylation
regulation of actin cytoskeleton organization
regulation of GTPase activity
ephrin receptor signaling pathway
regulation of focal adhesion assembly
regulation of microtubule cytoskeleton organization
cellular response to retinoic acid
fasciculation of sensory neuron axon
fasciculation of motor neuron axon
endocardial cushion development
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
motor neuron axon guidance
phosphorylation
fever generation
response to lipopolysaccharide
response to cytokine
