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Phospho-KIF20A (Tyr869) Antibody (PA5-105438) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-KIF20A (Tyr869) in mouse heart tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-KIF20A (Tyr869) polyclonal antibody (Product # PA5-105438) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105438
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KIF20A(Accession O95235), corresponding to amino acid residues around phosphorylated Tyr869.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2816866
产品详细信息
Antibody detects endogenous levels of KIF20A only when phosphorylated at Tyr869.
靶标信息
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GG10_2; Kinesin-like protein 174; Kinesin-like protein KIF20A; Mitotic kinesin-like protein 2; MKlp2; RAB6 interacting, kinesin-like (rabkinesin6); Rab6-interacting kinesin-like protein; Rabkinesin-6
基因别名: AA415432; KIF20A; MKLP2; RAB6KIFL
UniProt ID: (Human) O95235, (Mouse) P97329
Entrez Gene ID: (Human) 10112, (Mouse) 19348, (Rat) 361308
