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Phospho-MAPRE3 (Ser162) Antibody (PA5-143684) in WB
Western blot of Phospho-MAPRE3 (Ser162) in adult mouse brain untreated (lanes 1, 3, 5, & 7) or treated with lambda phosphatase (lanes 2, 4, 6, & 8). The blots were probed with rat monoclonal anti-EB3 (lanes 1 & 2), and rabbit Phospho-MAPRE3 (Ser162) polyclonal antibody (Product # PA5-143684) (lanes 3 & 4), anti-EB3 (Ser176) (lanes 5 & 6), and anti-EB3 (a.a. 171-182) (lanes 7 & 8).
产品信息
PA5-143684
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Phospho-EB3 (Ser-162) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 162 in human EB3. This peptide sequence is highly conserved in mouse and rat EB3, and is not conserved in EB1 and EB2.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2942912
产品详细信息
The antibody detects a 32 kDa* protein corresponding to the apparent molecular mass of phosphorylated EB3 on SDS-PAGE immunoblots of mouse brain. This reactivity is significantly reduced after lambda phosphatase treatment.
靶标信息
EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APC binding protein; EB1 protein family member 3; EB3; EBF3; End-binding protein 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
基因别名: AI790651; EB2; EB3; EBF3; EBF3-S; MAPRE3; RP3
UniProt ID: (Human) Q9UPY8, (Mouse) Q6PER3, (Rat) Q5XIT1
Entrez Gene ID: (Human) 22924, (Mouse) 100732, (Rat) 298848
