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Invitrogen
Phospho-MARCKS (Ser167, Ser170) Recombinant Rabbit Monoclonal Antibody (MARCKSS167170-C9)
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Phospho-MARCKS (Ser167, Ser170) Antibody (MA5-37189) in WB
Western blot analysis of Phospho-MARCKS (Ser167, Ser170) using NIH3T3 cell extract. Samples were untreated or treated with TPA, and incubated in monoclonal Phospho-MARCKS (Ser167, Ser170) antibody (Product # MA5-37189) with a dilution of 0.1 µg/mL.
产品信息
MA5-37189
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
MARCKSS167170-C9
抗原
A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 0.10% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897123
靶标信息
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 80K protein; 80K-L protein; FLJ14368; FLJ90045; MARCKS; MARCS; Myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; protein kinase C substrate 80 kDa protein; Protein kinase C substrate, 80 kDa protein, light chain
基因别名: 80K-L; KINC; MACS; MARCKS; PKCSL; PRKCSL
UniProt ID: (Human) P29966, (Mouse) P26645
Entrez Gene ID: (Human) 4082, (Rat) 25603, (Mouse) 17118
ventricular cardiac muscle tissue development
intracellular protein transport
actin filament organization
brain development
positive regulation of neuron projection development
activation of phospholipase D activity
cell-substrate adhesion
positive regulation of dendritic spine morphogenesis
positive regulation of protein kinase C activity
positive regulation of glucose import in response to insulin stimulus
regulation of insulin secretion
