Invitrogen

Phospho-MARK1/MARK2/MARK3 (Thr215, Thr208, Thr234) Polyclonal Antibody

高级验证

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

7个已发表图片

5 篇参考文献

说明书

实验方案

技术支持

说明书

实验方案

技术支持

Phospho-MARK1/MARK2/MARK3 (Thr215, Thr208, Thr234) Antibody in Western Blot (WB)

图: 1 / 10

Phospho-MARK1/MARK2/MARK3 (Thr215, Thr208, Thr234) Antibody (PA5-17495) in WB

Western blot analysis of Phospho-MARK Family in extracts from Raji and BaF3 cells showing endogenous levels of phosphorylated MARK family members using Phospho-MARK Family polyclonal antibody (Product # PA5-17495).

Phospho-MARK1/MARK2/MARK3 (Thr215, Thr208, Thr234) Antibody in Immunohistochemistry (IHC)

Phospho-MARK1/MARK2/MARK3 (Thr215, Thr208, Thr234) Antibody

Product Image Gallery

产品信息

PA5-17495

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看3篇已发表文章 3篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic phosphopeptide corresponding to residues surrounding threonine 215 of human MARK1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

59 µg/mL

纯化类型

Antigen affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

no preservative

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_10980994

产品详细信息

This antibody does not react with MARK4.

It is not recommended to aliquot this antibody.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Henderson MX,Chung CH,Riddle DM,Zhang B,Gathagan RJ,Seeholzer SH,Trojanowski JQ,Lee VMY

PA5-17495 was used in Immunocytochemistry to support a role for autophagy as a survival mechanism in response to stress due to ribosomal P proteins protein deficiency.

Wed Jun 14 00:00:00 EDT 2017

Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression.

Nature communications

Dogliotti G,Kullmann L,Dhumale P,Thiele C,Panichkina O,Mendl G,Houben R,Haferkamp S,Püschel AW,Krahn MP

PA5-17495 was used in Western Blot to show that targeting of the kinase to the membrane by a direct binding of LKB1 to phosphatidic acid is essential to fully activate its kinase activity.

Mon Jun 26 00:00:00 EDT 2017

Postsynaptic density 95 (PSD-95) serine 561 phosphorylation regulates a conformational switch and bidirectional dendritic spine structural plasticity.

The Journal of biological chemistry

Wu Q,Sun M,Bernard LP,Zhang H

PA5-17495 was used in Western Blotting to reveal insight into the regulation of PSD-95 in dendritic spine structural plasticity through phosphorylation-mediated regulation of protein dynamics and conformation.

Fri Sep 29 00:00:00 EDT 2017

MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism.

PloS one

Bernard LP,Zhang H

Published figure using Phospho-MARK1/MARK2/MARK3 (Thr215, Thr208, Thr234) polyclonal antibody (Product # PA5-17495) in Western Blot

Wed Jan 27 00:00:00 EST 2016

MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer's disease granulovacuolar degeneration bodies.

Acta neuropathologica communications

Lund H,Gustafsson E,Svensson A,Nilsson M,Berg M,Sunnemark D,von Euler G

PA5-17495 was used in immunohistochemistry to study the significance for Alzheimer's disease of the presence in granulovacuolar degradation bodies of MARK-3/MARK-4 and Ser262 phosphorylated tau

Mon Feb 17 00:00:00 EST 2014

生物信息学

蛋白别名: C-TAK1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 1; ELKL motif kinase 2; ELKL motif serine-threonine protein kinase 3; ELKL motif serine/threonine-protein kinase 3; EMK-1; EMK-2; EMK1; EMK2/MARK3 serine-threonine protein kinase; MAP/microtubule affinity-regulating kinase 1; MAP/microtubule affinity-regulating kinase 2; MAP/microtubule affinity-regulating kinase 3; MARK1; mark1 {ECO:0000312|RGD:619882}; MARK2; mark2 {ECO:0000312|RGD:708483}; MPK-10; Par-1a; Par-1b; Par-1c; PAR1 homolog; PAR1 homolog b; PAR1 homolog c; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Ser/Thr protein kinase PAR-1B; serine/threonine kinase; serine/threonine protein kinase EMK; Serine/threonine-protein kinase MARK1; Serine/threonine-protein kinase MARK2; Serine/threonine-protein kinase p78; testicular tissue protein Li 117

查看更多收起

基因别名: 1600015G02Rik; A430080F22Rik; AW491150; B930025N23Rik; C-TAK1; CTAK1; Emk; EMK-1; EMK1; EMK2; Emk3; ETK-1; ETK1; KIAA1477; KP78; MARK; MARK1; MARK2; MARK3; mKIAA1477; mPar-1c; MPK10; PAR-1; Par-1a; Par-1b; Par-1c; PAR1A; Par1b; Par1c