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Phospho-NFATC4 (Ser289) Antibody (PA5-105650) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-NFATC4 (Ser289) in mouse kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-NFATC4 (Ser289) polyclonal antibody (Product # PA5-105650) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105650
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NFATC4(Accession Q14934), corresponding to amino acid residues around phosphorylated Ser289.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2817078
产品详细信息
Antibody detects endogenous levels of NFAT3 only when phosphorylated at Ser289.
靶标信息
This protein is an adapter or scaffold protein, which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NF-AT3; NF-ATc4; NFATc4; Nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3; transcription complex subunit NF-ATc4
基因别名: 3110041H08Rik; AW107667; AW546455; NF-AT3; NF-ATC4; NFAT3; NFATC4
UniProt ID: (Human) Q14934, (Mouse) Q8K120, (Rat) D3Z9H7
Entrez Gene ID: (Human) 4776, (Mouse) 73181, (Rat) 305897
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription coactivator activity
protein binding
transcription factor binding
peroxisome proliferator activated receptor binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
Rel homology transcription factor
patterning of blood vessels
transcription from RNA polymerase II promoter
inflammatory response
heart development
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of Wnt signaling pathway
negative regulation of protein binding
positive regulation of tumor necrosis factor production
calcineurin-NFAT signaling cascade
cellular response to UV
negative regulation of chromatin binding
cellular respiration
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
smooth muscle cell differentiation
muscle cell development
cellular response to lithium ion
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of synapse maturation
positive regulation of apoptotic signaling pathway
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
cell differentiation
positive regulation of apoptotic process
