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Antibody detects endogenous levels of NuMA only when phosphorylated at Ser395.
NuMA (nuclear mitotic apparatus) is a long coil-coiled protein that plays a role in the interphase and mitosis phases of a cell cycle. In interphase, it has been hypothesized to play a structural role in the nucleoskeleton that may be important in nuclear organization and functions. During mitosis, it is associated with spindle microtubule organization and chromosome positioning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: centrophilin stabilizes mitotic spindle in mitotic cells; NMP-22; Nuclear matrix protein-22; Nuclear mitotic apparatus protein; Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen; structural nuclear protein
基因别名: 6720401E04Rik; AA764025; AL022610; AU014979; NMP-22; NMP22; NUMA; NUMA1
UniProt ID: (Human) Q14980, (Mouse) E9Q7G0
Entrez Gene ID: (Human) 4926, (Rat) 308870, (Mouse) 101706