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Phospho-PEA15 (Ser104) Antibody (PA5-97398) in WB
Western blot analysis of Phospho-PEA15 (Ser104) in extracts of HeLa and C6 cells. Samples were incubated with Phospho-PEA15 (Ser104) Polyclonal antibody (Product # PA5-97398) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. HeLa cells were treated by PMA/TPA (200 nM) for 15 minutes after serum-starvation overnight. C6 cells were treated by... View More
产品信息
PA5-97398
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic phosphorylated peptide around S104 of human PEA15 (NP_0037591)
偶联物
Unconjugated
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2809200
产品详细信息
Immunogen sequence: IPSAK; Positive Samples: HeLa, C6; Cellular Location: Cytoplasm
靶标信息
PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 15 kDa phosphoprotein enriched in astrocytes; Astrocytic phosphoprotein PEA-15; homolog of mouse MAT-1 oncogene; mammary transforming gene 1; mammary transforming gene 1, mouse, homolog of; OTTHUMP00000029887; PED; phosphoprotein enriched in astrocytes 15; phosphoprotein enriched in astrocytes 15A; Phosphoprotein enriched in diabetes
基因别名: HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PEA15; Pea15a; PED; Pkcs15
UniProt ID: (Human) Q15121, (Rat) Q5U318, (Mouse) Q62048
Entrez Gene ID: (Human) 8682, (Rat) 364052, (Mouse) 18611
DNA damage checkpoint
MAPK cascade
activation of MAPK activity
transport
apoptotic process
carbohydrate transport
response to morphine
negative regulation of glucose import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
intracellular signal transduction
regulation of apoptotic process
