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Phospho-PLD1 (Ser561) Antibody (PA5-105636) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-PLD1 (Ser561) in human kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-PLD1 (Ser561) polyclonal antibody (Product # PA5-105636) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-105636
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PLD1(Accession Q13393), corresponding to amino acid residues around phosphorylated Ser561.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2817064
产品详细信息
Antibody detects endogenous levels of PLD1 only when phosphorylated at Ser561.
靶标信息
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Choline phosphatase 1; hPLD1; mPLD1; phophatidylcholine-specific; Phoshpolipase D gene 1 probably with two splicing variants A and B; Phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D gene 1, probably with two splicing variants A and B; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1; rPLD1
基因别名: AA536939; C85393; PLD1; Pld1a; Pld1b; Plda; Pldb
UniProt ID: (Human) Q13393, (Rat) P70496
Entrez Gene ID: (Human) 5337, (Rat) 25096, (Mouse) 18805
phosphatidic acid biosynthetic process
chemotaxis
small GTPase mediated signal transduction
Ras protein signal transduction
lipid catabolic process
regulation of microvillus assembly
inositol lipid-mediated signaling
cell motility
metabolic process
phospholipid biosynthetic process
phospholipid catabolic process
positive regulation of cell migration
response to peptide hormone
defense response to Gram-positive bacterium
lipid metabolic process
regulation of cell migration
regulation of phagocytosis
