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Application
产品信息
600-401-447
应用
建议稀释比
已发表文章
产品规格
种属反应
Yeast
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to an internal region near aa 110-135 (of 273) of yeast DNA Replication Factor A (RFA2).
偶联物
Unconjugated
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Affinity chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
内含物
0.01% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This affinity purified antibody is directed against yeast RFA2. This phospho specific polyclonal antibody is specific for phosphorylated pS122 of yeast RFA2. Reactivity with non-phosphorylated yeast RFA2 is minimal by ELISA.
靶标信息
Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication. [Uniprot]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA-binding protein BUF1; Replication factor A protein 2; Replication protein A 36 kDa subunit; RF-A protein 2
基因别名: BUF1; N0368; RFA2; RPA2; RPA32; YNL312W
UniProt ID: (Baker's yeast) P26754
Entrez Gene ID: (Baker's yeast) 855404
telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA replication
DNA topological change
DNA unwinding involved in DNA replication
DNA repair
nucleotide-excision repair
DNA recombination
mitotic recombination
telomere maintenance via telomerase
reciprocal meiotic recombination
telomere maintenance via telomere lengthening
protein ubiquitination
heteroduplex formation
establishment of protein localization
