Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-RelB (Ser552) Recombinant Rabbit Monoclonal Antibody (RelBS552-A7), PE
Application
图: 1 / 1
Phospho-RelB (Ser552) Antibody (MA5-37031) in Flow
Flow cytometry of Phospho-RelB (Ser552) using NIH3T3 cells. Samples were incubated in monoclonal Phospho-RelB (Ser552) antibody (Product # MA5-37031). Images correspond with the following conditions: untreated, unstained negative control (blue), untreated (red), treated with UV plus TPA (green).
产品信息
MA5-37031
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RelBS552-A7
抗原
A synthetic phospho-peptide corresponding to residues surrounding Ser552 of human phospho RelB.
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
纯化类型
Protein A/G
保存液
PBS with 0.20% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2896966
靶标信息
The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFkB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFkB homodimers. However, Rel B/p50 heterodimers, in contrast to NFkB heterodimers, transactivates transcription of promotors containing kB binding sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Video Player is loading.
Current Time 0:00
Duration 8:21
Loaded: 1.98%
Stream Type LIVE
Remaining Time 8:21
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: I-Rel; OTTHUMP00000221313; rel b; Transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
基因别名: I-REL; IREL; REL-B; RELB; shep
UniProt ID: (Human) Q01201, (Mouse) Q04863
Entrez Gene ID: (Human) 5971, (Mouse) 19698
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
Rel homology transcription factor
negative regulation of transcription from RNA polymerase II promoter
stimulatory C-type lectin receptor signaling pathway
transcription, DNA-templated
inflammatory response
I-kappaB kinase/NF-kappaB signaling
antigen processing and presentation
negative regulation of interferon-beta production
circadian regulation of gene expression
response to cytokine
NIK/NF-kappaB signaling
myeloid dendritic cell differentiation
T-helper 1 cell differentiation
innate immune response
positive regulation of transcription from RNA polymerase II promoter
cellular response to osmotic stress
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of gene expression
T-helper 1 type immune response
negative regulation of transcription, DNA-templated
rhythmic process
