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Phospho-STK38/STK38L (Thr444, Thr442) Antibody (PA5-99570) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-STK38 (Thr444, Thr442) in mouse kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-STK38 (Thr444, Thr442) polyclonal antibody (Product # PA5-99570) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-99570
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human STK38(Accession Q15208), corresponding to amino acid residues around phosphorylated Thr444.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2818503
产品详细信息
Antibody detects endogenous levels of NDR1/2 only when phosphorylated at Thr444/442.
靶标信息
This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ndr Ser/Thr kinase-like protein; NDR1 protein kinase; NDR2 protein kinase; nuclear Dbf2-related 2; Nuclear Dbf2-related kinase 1; Nuclear Dbf2-related kinase 2; serine/threonine kinase 38-like; Serine/threonine-protein kinase 38; Serine/threonine-protein kinase 38-like; stk38; STK38L
基因别名: 4930473A22Rik; 5830476G13Rik; 9530097A09Rik; AA617404; B230328I19; KIAA0965; NDR; NDR1; NDR2; Ndr54; RGD1564793; STK38; STK38L
UniProt ID: (Human) Q15208, (Human) Q9Y2H1, (Mouse) Q91VJ4, (Mouse) Q7TSE6
Entrez Gene ID: (Human) 11329, (Human) 23012, (Mouse) 106504, (Rat) 361813, (Mouse) 232533, (Rat) 691337
magnesium ion binding
protein serine/threonine kinase activity
protein binding
ATP binding
mitogen-activated protein kinase kinase kinase binding
cadherin binding involved in cell-cell adhesion
actin binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
molecular_function
non-receptor serine/threonine protein kinase
