Invitrogen

Profilin 2 Polyclonal Antibody

Profilin 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Profilin 2 Antibody (PA5-21959) in IHC (P)

Profilin 2 Polyclonal Antibody detects PFN2 protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. Profilin 2 Polyclonal Antibody (Product # PA5-21959) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

Profilin 2 Antibody in Western Blot (WB)

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产品信息

PA5-21959

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 90 (P35080) of Profilin 2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_11153817

产品详细信息

Recommended positive controls: A431, H1299, mouse brain, rat brain.

Predicted reactivity: Mouse (94%), Rat (91%), Chicken (93%), Bovine (94%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Downregulation of circATXN7 represses non-small cell lung cancer growth by releasing miR-7-5p.

Thoracic cancer

Li D,Fu Z,Dong C,Song Y

PA5-21959 was used in Immunohistochemistry (Paraffin), Western Blot to conclude that CircATXN7 accelerated the malignancy of NSCLC cells through adsorbing miR-7-5p and upregulating PFN2, offering evidence to support circATXN7 as a target for NSCLC treatment.