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Positive Samples: A-549, HT-29, Raji, B cells, Mouse spleen, Mouse lung, Mouse skeletal muscle, Rat spleen
Immunogen sequence: TQTPSVYDES GSTGGGDDST PSILPAPRGY PGQVCANDSD TLELPDSSRA LLLGWVPTRL VPALYGLVLV VGLPANGLAL WVLATQAPRL PSTMLLMNLA AADLLLALAL PPRIAYHLRG QRWPFGEAAC R
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; PAR-4; protease-activated receptor 4; protease-activated receptor-4; Proteinase-activated receptor 4; Thrombin receptor-like 3
基因别名: F2RL3; PAR4
UniProt ID: (Human) Q96RI0, (Rat) Q920E0, (Mouse) O88634
Entrez Gene ID: (Human) 9002, (Rat) 116498, (Mouse) 14065
分子生物学功能: G-protein coupled receptor