Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 9
Protein S Antibody (PA5-106880) in ICC/IF
Immunocytochemistry analysis of Protein S in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Protein S polyclonal antibody (Product # PA5-106880) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated g... View More
产品信息
PA5-106880
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PROS1(Accession P07225), corresponding to amino acid residues R38-C88.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854544
产品详细信息
Antibody detects endogenous levels of total PROS1.
靶标信息
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S
基因别名: AW214361; PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
UniProt ID: (Human) Q7Z715, (Mouse) Q08761
Entrez Gene ID: (Human) 5627, (Rat) 81750, (Mouse) 19128
platelet degranulation
signal peptide processing
ER to Golgi vesicle-mediated transport
blood coagulation
negative regulation of endopeptidase activity
peptidyl-glutamic acid carboxylation
regulation of complement activation
response to lipopolysaccharide
fibrinolysis
positive regulation of phagocytosis
leukocyte migration
negative regulation of coagulation
hemostasis
