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QKI-7 Antibody (75-200) in IHC (F)
Double immunofluorescence revealing pruned Lewy Neurites (pSyn, Red) and the cytoplasms of mature mouse OLs (QKI-7, cat. 75-200, 1:500; green) at the level of the anterior commissure of a mouse 6 months after the intrastriatal injection of alpha--Syn PFFs. Horizontal brain section. Nuclei are counterstained with DRAQ7 (white). Image from publication CC-BY-4.0. PMID:36830639.
产品信息
75-200
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N183/15
抗原
Synthetic peptide amino acids 303-317 of human QKI-7 (accession number Q96PU8-5).
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: LEWIEMPVMP DISAH
靶标信息
QKI-7 is an isoform of the Quaking (QKI) protein, which belongs to the STAR (Signal Transduction and Activation of RNA) family of RNA-binding proteins. QKI proteins play essential roles in RNA metabolism, including RNA splicing, stabilization, and translation, and are crucial for various cellular processes. QKI-7 is an important RNA-binding protein with significant roles in the nervous system, particularly in the regulation of myelination and neuronal RNA processing. Its study is essential for understanding the molecular basis of various neurological disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homolog of mouse quaking QKI (KH domain RNA binding protein); Hqk; KH domain-containing RNA-binding protein QKI; lethal, Chr 17, U Wisconsin 1; MqkI; Protein quaking; QKI, KH domain containing, RNA binding; QKI-5 protein; quaking homolog, KH domain RNA binding; RNA binding protein HQK
基因别名: 1110003F05Rik; 1500005P18; HKQ; Hqk; hqkI; l(17)-1Wis; l17Wis1; QK; QK1; QK3; QKI
UniProt ID: (Human) Q96PU8, (Mouse) Q9QYS9
Entrez Gene ID: (Human) 9444, (Mouse) 19317
vasculogenesis
mRNA processing
spermatid development
RNA splicing
positive regulation of gene expression
myelination
muscle cell differentiation
long-chain fatty acid biosynthetic process
mRNA transport
3'-UTR-mediated mRNA destabilization
regulation of translation
transport
multicellular organism development
axon ensheathment
cell differentiation
