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Peptide sequence: SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA
Sequence homology: Cow: 86%; Dog: 79%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 100%; Sheep: 86%
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EC; Glutaminyl cyclase; Glutaminyl-peptide cyclotransferase; Glutaminyl-tRNA cyclotransferase; Glutamyl cyclase; QC
基因别名: GCT; QC; QPCT; sQC
UniProt ID: (Human) Q16769
Entrez Gene ID: (Human) 25797
分子生物学功能: transferase