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Positive test controls include: NCI-H460, U-251MG, Mouse heart. The target is usually found in the following locations: Golgi apparatus membrane, Secreted, Single-pass membrane protein, extracellular space.
Immunogen sequence: MRRCNSGSGP PPSLLLLLLW LLAVPGANAA PRSALYSPSD PLTLLQADTV RGAVLGSRSA WAVEFFASWC GHCIAFAPTW KALAEDVKAW RPALYLAALD CAEETNSAVC RDFNIPGFPT VRFFKAFTKN GSGAVFPVAG ADVQTLRERL IDALESHHDT WPPACPPLEP AKLEEIDGFF ARNNEEYLAL IFEKGGSYLG REVALDLSQH KGVAVRRVLN TEANVVRKFG VTDFPSCYLL FRNGSVSRVP VLMESRSFYT AYLQRLSGLT REAAQTTVAP TTANKIAPTV WKLADRSKIY MADLESALHY ILRIEVGRFP VLEGQRLVAL
The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia and appears to protect cells against oxidative stress-induced apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hQSOX; mSOx; Quiescin Q6; quiescin Q6 sulfhydryl oxidase 1; RP11-502H18.3; Skin sulfhydryl oxidase; Sulfhydryl oxidase 1; testis tissue sperm-binding protein Li 62n; thiol oxidase 1
基因别名: 1300003H02Rik; Q6; QSCN6; QSOX; QSOX1; SOx; UNQ2520/PRO6013
UniProt ID: (Human) O00391, (Mouse) Q8BND5
Entrez Gene ID: (Human) 5768, (Mouse) 104009
分子生物学功能: oxidase