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Recommended positive controls: NT2D1, PC-3.
Predicted reactivity: Mouse (89%), Rat (91%), Zebrafish (81%), Xenopus laevis (83%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
tRNA-guanine transglycosylase (TGT; EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14; MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Guanine insertion enzyme; queuine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 1; Queuine tRNA-ribosyltransferase catalytic subunit 1; TGT, 43-KD subunit; TGT, catalytic subunit; tRNA-guanine transglycosylase
基因别名: 2610028E17Rik; FP3235; QTRT1; TGT; TGUT
UniProt ID: (Human) Q9BXR0, (Mouse) Q9JMA2
Entrez Gene ID: (Human) 81890, (Mouse) 60507
分子生物学功能:
RNA metabolism protein
RNA processing factor
nucleic acid metabolism protein