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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: putative Ras-related protein Rab-12; Ras-related protein Rab-12
基因别名: RAB12
UniProt ID: (Human) Q6IQ22
Entrez Gene ID: (Human) 201475