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RAB1B Antibody (MA5-31880) in IHC (P)
Immunohistochemistry analysis of RAB1B in paraffin-embedded esophageal cancer tissue. Sample was incubated with RAB1B monoclonal antibody (Product # MA5-31880) using a dilution of 1:200-1:1000 followed by DAB staining.
产品信息
MA5-31880
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
7A12G2
抗原
Purified recombinant fragment of human Rab1b (AA: 60-201) expressed in E. coli.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787503
产品详细信息
MA5-31880 has been tested in indirect ELISA.
靶标信息
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ras-related protein Rab-1B; small GTP-binding protein
基因别名: RAB1B
UniProt ID: (Human) Q9H0U4
Entrez Gene ID: (Human) 81876
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
autophagy
small GTPase mediated signal transduction
protein transport
virion assembly
COPII vesicle coating
establishment of endothelial intestinal barrier
positive regulation of glycoprotein metabolic process
regulation of autophagosome assembly
