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Product Details
PA5-46057
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human RAB3GAP2
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2605453
Product Specific Information
Peptide sequence: SWLQDCVLSL SPTNDLMVIA REQKAVFLVP KWKYSDKGKE EMQFAVGWSG
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 86%; Rat: 93%
Target Information
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; Rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; Rab3-GAP150; RGAP-iso
Gene Aliases: KIAA0839; p150; RAB3-GAP150; RAB3GAP150; RAB3GAP2; SPG69; WARBM2
UniProt ID: (Human) Q9H2M9
Entrez Gene ID: (Human) 25782
intracellular protein transport
regulation of GTPase activity
positive regulation of GTPase activity
establishment of protein localization to endoplasmic reticulum membrane
positive regulation of protein lipidation
positive regulation of endoplasmic reticulum tubular network organization
positive regulation of autophagosome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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