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产品信息
H00117177-B01P
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RAB3IP (NP_071901.2, 1 a.a. approximately 460 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MANDPLEGFH EVNLASPTSP DLLGVYESGT QEQTTSPSVI YRPHPSALSS VPIQANALDV SELPTQPVYS SPRRLNCAEI SSISFHVTDP APCSTSGVTA GLTKLTTRKD NYNAEREFLQ GATITEACDG SDDIFGLSTD SLSRLRSPSV LEVREKGYER LKEELAKAQR ELKLKDEECE RLSKVRDQLG QELEELTASL FEEAHKMVRE ANIKQATAEK QLKEAQGKID VLQAEVAALK TLVLSSSPTS PTQEPLPGGK TPFKKGHTRN KSTSSAMSGS HQDLSVIQPI VKDCKEADLS LYNEFRLWKD EPTMDRTCPF LDKIYQEDIF PCLTFSKSEL ASAVLEAVEN NTLSIEPVGL QPIRFVKASA VECGGPKKCA LTGQSKSCKH RIKLGDSSNY YYISPFCRYR ITSVCNFFTY IRYIQQGLVK QQDVDQMFWE VMQLRKEMSL AKLGYFKEEL
靶标信息
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Rab-3A-interacting protein; RAB3A-interacting protein; RAB3IP; rab3ip {ECO:0000250|UniProtKB:Q96QF0}; rabin 3; Rabin-3; Rabin8; SSX2 interacting protein; SSX2-interacting protein
基因别名: RAB3IP; RABIN3; RABIN8
UniProt ID: (Human) Q96QF0, (Rat) Q62739
Entrez Gene ID: (Human) 117177, (Rat) 29885
