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RAB3IP Antibody (PA5-99698) in IHC (P)
Immunohistochemistry analysis of RAB3IP in mouse liver tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with RAB3IP polyclonal antibody (Product # PA5-99698) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-99698
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RAB3IP(Accession Q96QF0), corresponding to amino acid residues L260-C310.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2818631
产品详细信息
Antibody detects endogenous levels of total RAB3IP.
靶标信息
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: gene trap PAT 12; Rab-3A-interacting protein; RAB3A-interacting protein; RAB3IP; rab3ip {ECO:0000250|UniProtKB:Q96QF0}; rabin 3; Rabin-3; Rabin8; SSX2 interacting protein; SSX2-interacting protein
基因别名: B230311A06; Gtpat12; RAB3IP; RABIN3; RABIN8
UniProt ID: (Human) Q96QF0, (Rat) Q62739, (Mouse) Q68EF0
Entrez Gene ID: (Human) 117177, (Rat) 29885, (Mouse) 216363
