Invitrogen

RAC1 Polyclonal Antibody

RAC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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RAC1 Antibody (PA5-44839) in IHC (P)

Immunohistochemistry (paraffin-embedded) analysis of human adult colon tissue using an anti-Rac1 / cdc42 polyclonal antibody (Product # PA5-44839).

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产品信息

PA5-44839

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:600

产品规格

种属反应

Human

已发表种属

Rat, Zebrafish

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human RAC1

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2608339

产品详细信息

Peptide sequence: LAMAKEIGAV KYLECSALTQ RGLKTVFDEA IRAVLCPPPV KKRKRKCLLL

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

靶标信息

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Dephosphorylation of Y228 and Y217 and phosphorylation of Y335 in p120 catenin activate convergent extension during zebrafish gastrulation.

Developmental dynamics : an official publication of the American Association of Anatomists

Shan B,Horton EC,Xu SC,Huntington KE,Kawano DK,Mendoza CL,Lin L,Stafford CM,Allen ED,Huang J,Nakahara H,Greenstein LE,Hille MB

PA5-44839 was used in Immunohistochemistry (Paraffin), Western Blot to show that p120 catenin serves dual roles during gastrulation of zebrafish and phosphorylation and dephosphorylation of tyrosine residues Y217, Y228, and Y335 precisely balance cell adhesion and cell migration to facilitate somite compaction and axis elongation.

Thu Dec 01 00:00:00 EST 2022

Dephosphorylation of Y228 and Y217 and phosphorylation of Y335 in p120 catenin activate convergent extension during zebrafish gastrulation.

Developmental dynamics : an official publication of the American Association of Anatomists

Shan B,Horton EC,Xu SC,Huntington KE,Kawano DK,Mendoza CL,Lin L,Stafford CM,Allen ED,Huang J,Nakahara H,Greenstein LE,Hille MB

Thu Dec 01 00:00:00 EST 2022

The PKGIα-Rac1 pathway is a novel regulator of insulin-dependent glucose uptake in cultured rat podocytes.

Journal of cellular physiology

Audzeyenka I,Rogacka D,Rachubik P,Typiak M,Rychłowski M,Angielski S,Piwkowska A

PA5-44839 was used in Immunohistochemistry (Paraffin), Western Blot to provide evidence that PKGIα (protein kinase G type Iα)-dependent activation of the Rac1 signaling pathways is a novel regulator of insulin-mediated glucose uptake in cultured rat podocytes.