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产品信息
PA5-148285
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human RAC3 fragment
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTMUSP00000004488; p21 Rac3; p21-Rac3; Rac1B; RAC3; RAC3_HUMAN; RAS related C3 botulinum substrate 3; Ras related C3 botulinum toxin substrate 3; Ras-related C3 botulinum toxin substrate 3; Rho family small GTP binding protein Rac3; rho family, small GTP binding protein Rac3; RP23-84C12.18
基因别名: RAC3
UniProt ID: (Human) P60763
Entrez Gene ID: (Human) 5881
small GTPase mediated signal transduction
regulation of neuron maturation
cerebral cortex GABAergic interneuron development
cell projection assembly
actin cytoskeleton organization
neuron projection development
positive regulation of cell adhesion mediated by integrin
intracellular signal transduction
homeostasis of number of cells within a tissue
neuromuscular process controlling balance
regulation of small GTPase mediated signal transduction
synaptic transmission, GABAergic
positive regulation of substrate adhesion-dependent cell spreading
