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Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ral guanine nucleotide dissociation stimulator; Ral guanine nucleotide exchange factor; RalGDS; RalGEF
基因别名: KIAA1308; RALGDS; RalGEF; RGDS; RGF
UniProt ID: (Human) Q12967
Entrez Gene ID: (Human) 5900
分子生物学功能:
guanyl-nucleotide exchange factor